Monday, February 21, 2011

Relaxation only lasts so long



We're back from a lovely week in Hawaii. It was very low-key. I snorkeled one morning, but otherwise read by the beach or pool while my husband snorkeled, body surfed, and scuba dived. I'm certified for scuba, but am nervous about ocean dives, so I decided to skip it.

The weather was great, which is one of the predictable things about Hawaii. We didn't even get any rain during our week. At home in California it was rainy and cold. And is still really cold, but not raining until the weekend. (Really cold = highs in the low 50s -- you snow-bound folks can now laugh at me.)

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For those of you who have been following along, I expected to have a monitoring appointment on Sunday and start stims on Monday. Well, that was based on AF coming before/during my vacation. Which it didn't.

I'm annoyed, because I told my clinic that I was very uncertain about when my last period was, and they said it really didn't matter. I now suspect that the bleeding that finally ended at the beginning of February was probably the end of AF. Which means starting estrace on February 7 was probably pre-ovulation, as was the Ganirelix.

No idea what that means for priming my follies, but I rather suspect it isn't good. I emailed my RE on Thursday night (from Hawaii) and my clinic relayed that he said to keep taking the Estrace.

I'm mildly annoyed at my body for not being easier to read, and more annoyed with the clinic for not listening to me. A blood test could have indicated where in my cycle I was.

Now I have no way to estimate when retrieval and transfer will be. If the estrogen priming cycle was wasted, that would push us back an entire month. If it wasn't wasted, then it'll depend on when AF shows. Today would have been counted as CD2 if I'd started stims.

Grr.

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I'm having some trouble reading new baby blogs and tweets right now. Please don't take it personally if I stop reading/commenting, it's just not where my head is at, and I'm trying to avoid the negative feelings that sometimes/often arise. I'm thrilled for those of you that made it to the finish line.

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amiracle4us asked about my immune treatment in the comments of my last post...

For IVF #1, we did two shots of Humira, two weeks apart, pre-stims, and then did Intralipids starting with a positive pregnancy test (so roughly 4 weeks and 7 weeks). Before the treatment, my RE rated my NK levels as a 4/5 (where 5/5 is worst, and 0/5 is normal). After the Humira I was down to a 1/5.

For IVF #2, we did Intralipids -- one pre retrieval during stims, and then none after because of the cancelled cycle.

For IVF #3, we did two shots of Humira, two weeks apart, pre-stims (bloodwork a week after the shots got me to a 0/5 -- completely normal NK and TH1:TH2 levels), an Intralipid with retrieval , another after the positive pregnancy test, and had another scheduled for 3 weeks later. When I had the first ultrasound with my ob/gyn, it was a day or two before the scheduled Intralipid. Because the heartbeat was low, he did an unplanned Intralipid right after the ultrasound in case immunological factors were involved in killing off the embryo. (Which turned out not to be the case - it was a chromosonal abnormality.)

I asked my RE why he wanted to do an Intralipid with retrieval even though I was showing completely normal NK and TH1:TH2 levels, and he said it's easier to stay ahead of things instead of being reactive to increasing levels.

IVF #4 has involved the 2 shots of Humira during what's hopefully my estrogen priming cycle, and I'll repeat the bloodwork after AF to see if my levels are normal or not.

Hope that helps!

9 comments:

  1. Ahh I'm pleased you had a lovely week away. So sorry though to hear that AF didn't show when she should have done (typical), I hope that your cycle can be saved so you can keep progressing along.
    Take all the time you need, we'll all still be here for you.

    Sending you hugs,
    Moon x

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  2. I'm so glad you had a nice vacation in Hawaii! And yes, to a snow bound chica like myself highs in the 50s sounds amazing!! The high is 30 here and I'm sick of it :-).

    I hope that all works out for this cycle. I definitely understand needing to shield yourself from parenting/pregnancy blogs, take all the time you need!

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  3. What a wonderful vacation - so glad you had this time away! And I'm sending you good thoughts that your body figures itself out and starts cooperating!

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  4. I am so happy you had a great trip...I hope AF comes soon and you can move forward :) I understand the difficulty with reading new baby blogs...sometimes it is so much harder than other times.

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  5. you are so right how fast the calm of vaca leaves us. so sad.
    I hope your body gets regulated soon.
    thanks for the tips today, you are so helfpul!!!

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  6. Sorry to hear your cycle isn't cooperating with you but hang in there! Read blogs that inspire you and keep relaxed and I'm sure you'll get that BFP before you know it :-)

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  7. Glad you had a lovely break, sounds very relaxing - and am so jealous about the weather. We really have got it ad here in the UK.

    Sorry AF didn't show up in time but I'm hoping you can stick with this cycle.

    I've given your blog a reward on my blog - see http://myttcstory.com/?p=171

    Sending you luck & hugs,
    MyTTC

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  8. Sadly, the relaxation bubble can POP in just a second...but hopefully you can find that space in your head again. And, COME ON AF!! LET'S GET GOING!!!

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  9. Being in the dark about our own bodies is one of the hardest things...I know how you feel. I really hope you get some answers soon and are able to get started.

    Thanks for your comment on my blog. I look forward to reading more about you :)

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